Description
What Is NAD+? (In Plain English)
NAD+ is a small helper molecule that cells use to pass energy around, a bit like a bucket in a bucket brigade: it picks up electrons in one place and hands them off in another. Nearly every cell needs it, and the amount inside cells changes with age and stress. Scientists study NAD+ in cells and animals to see how those bucket levels shift and what depends on them.
NAD+ — Research Overview
NAD+ (nicotinamide adenine dinucleotide, oxidised form) is a pyridine dinucleotide coenzyme, not a peptide, composed of nicotinamide mononucleotide linked to adenosine monophosphate. The literature describes it as the central redox carrier of glycolysis, the TCA cycle and oxidative phosphorylation, and as the obligatory substrate consumed by sirtuins, PARPs and CD38 in non-redox signalling reactions. Research interest centres on the NAD+ salvage pathway and on how cellular NAD+/NADH ratios track with metabolic state in model systems.
Primary Research Areas
- Redox biochemistry — NAD+/NADH ratio measured as a readout of cellular metabolic state
- Sirtuin signalling — investigated as the rate-limiting substrate for SIRT1–SIRT7 deacetylation in vitro
- DNA damage response — PARP-mediated NAD+ consumption studied in cell culture
- Mitochondrial function — examined in animal models of age-associated NAD+ decline
- Salvage pathway enzymology — NAMPT and NMNAT kinetics characterised using exogenous NAD+
Specifications
- Compound: NAD+; β-nicotinamide adenine dinucleotide (oxidised)
- CAS: 53-84-9
- Molecular formula: C21H27N7O14P2
- Molecular weight: ~663.4 g/mol
- Presentation: Lyophilized powder, sealed vial
- Quantity: One lyophilized vial per unit; fill weight as stated in the listing options
- Storage: Store lyophilized vials cold and protected from light. Reconstituted material is stored refrigerated per standard laboratory practice.
Related Research Compounds
Laboratories comparing fill weights generally order NAD+ 500mg or NAD+ 1000mg depending on assay scale. Adjacent cellular-energetics work commonly pairs NAD+ with MOTS-c and the antioxidant comparator Glutathione 1500mg.
Why Researchers Source NAD+ from Dissolv Labs
Dissolv Labs is a research-supply company based in Southern California. Orders are picked, packed, and shipped domestically from our SoCal facility, so most U.S. laboratories see short transit times and no international customs delay.
Every vial ships as a complete kit. Each NAD+ vial is paired with its own bacteriostatic water reconstitution vial, so the material arrives ready to prepare in the lab without a separate diluent order. Compounds are supplied lyophilized in sealed, labeled vials with lot identification, and analytical documentation is available on request.
NAD+ — Frequently Asked Questions
What is NAD+ used for?
NAD+ is supplied strictly as a research chemical for in vitro and laboratory research applications. The literature uses it as a redox cofactor and as the substrate for sirtuin, PARP and CD38 enzyme assays. It is not for human or veterinary use.
Is NAD+ a peptide?
No. NAD+ is a dinucleotide coenzyme built from nicotinamide and adenine ribonucleotides, with no amino acid content at all. It is catalogued alongside research peptides because laboratories studying cellular energetics and aging frequently work with both classes in the same experiments.
How is NAD+ handled once reconstituted?
Lyophilized NAD+ is stored cold and protected from light in its sealed vial. In aqueous solution the oxidised form is sensitive to alkaline pH and to repeated freeze–thaw cycles, so reconstituted stock is kept refrigerated and aliquoted per standard laboratory practice. A matched bacteriostatic water vial ships with every kit, with more available as BAC Water 3ml.
Where can I buy NAD+ for research?
NAD+ is for sale from Dissolv Labs and ships domestically from our Southern California facility with lot identification on every vial. Domestic fulfilment keeps transit short for U.S. laboratories and avoids customs handling. Purchases are limited to qualified researchers for Research Use Only applications.
Research Use Only
NAD+ is sold exclusively as a Research Use Only (RUO) chemical. It is not a drug, supplement, cosmetic, or food, and it is not intended for human or veterinary use, ingestion, injection, topical application, or any form of consumption. It is intended solely for licensed laboratory research by qualified professionals. Dissolv Labs makes no medical, therapeutic, or diagnostic claims of any kind. By purchasing, the buyer confirms they are a qualified researcher and accepts full responsibility for lawful handling, use, and disposal.
Bacteriostatic (BAC) water is included free with every order.
Specifications
- Form: Lyophilized (freeze-dried) powder, sealed vial
- Appearance: White to off-white
- Purity: ≥99%, verified by HPLC
- Identity: Confirmed by mass spectrometry
- Testing: Independent third-party laboratory, every batch
- Documentation: Batch-specific COA available on request
Exact quantity and concentration are listed in the product title and variant options above. The figures above are release specifications — the measured result for your particular lot is stated on its Certificate of Analysis.
Documentation & Testing
Every batch is tested before release. Testing covers four checks: identity by mass spectrometry, purity by HPLC against a ≥99% release threshold, content verification against the labelled mass, and batch release tied to a specific lot number.
To request the Certificate of Analysis for your vial, email us with your order number or the lot number printed on the label. We do not gate documentation behind a form or a purchase.
New to reading a COA? Our plain-English guide decodes every line, and the full process is documented on our Quality & Testing page.
Handling & Storage
Lyophilized peptides are relatively stable during transit. Arriving at room temperature is not cause for concern — the cold pack is a margin of safety rather than a pass/fail condition.
Sealed vials of lyophilized material are typically stored refrigerated or frozen and protected from light. Handling protocols for a specific compound are determined by the researcher and their institution; we supply the material and its documentation.
Shipping & Returns
Orders placed before the daily cut-off are dispatched the same business day from Southern California in insulated packaging with ice packs. Tracking is issued at dispatch.
If a shipment arrives damaged, if vial contents appear inconsistent with the specification, or if the lot number on your vial does not match the certificate we provide, contact us and we will resolve it.
Because these are temperature-sensitive laboratory materials, opened vials cannot be returned to stock.
Questions
Straight answers about documentation, shipping, and what Research Use Only means.