Description
What Is NAD+ 500mg? (In Plain English)
NAD+ is a tiny molecule that acts like a rechargeable battery inside cells: it gets loaded up with electrons in one reaction and unloaded in the next, over and over. Cells also spend it whenever certain repair and housekeeping enzymes do their work. This 500mg vial gives laboratories a measured amount of the dry powder to study those reactions.
NAD+ 500mg — Research Overview
NAD+ (β-nicotinamide adenine dinucleotide) is a pyridine dinucleotide coenzyme, not a peptide, consisting of nicotinamide and adenine ribonucleotides joined through a pyrophosphate bridge. Across the literature it serves two distinct roles: a recycled hydride carrier in central metabolism, and a stoichiometrically consumed substrate for NAD+-dependent enzymes including the sirtuins, PARPs and CD38. The 500mg fill is a common working size for cell-culture panels and moderate-scale enzyme assays.
Primary Research Areas
- Cellular bioenergetics — NAD+/NADH ratios tracked as a metabolic-state readout in cultured cells
- NAD+ salvage pathway — NAMPT and NMNAT enzymology characterised in vitro
- Sirtuin-dependent deacetylation — substrate-limited SIRT activity examined in biochemical assays
- Genomic stress models — PARP-driven NAD+ depletion studied after DNA damage in cell lines
- Comparative aging research — tissue NAD+ pools measured in animal models of age-related decline
Specifications
- Compound: NAD+; nicotinamide adenine dinucleotide (oxidised form)
- CAS: 53-84-9
- Molecular formula: C21H27N7O14P2
- Molecular weight: ~663.4 g/mol
- Presentation: Lyophilized powder, sealed vial
- Quantity: 500mg per vial
- Storage: Store lyophilized vials cold and protected from light. Reconstituted material is stored refrigerated per standard laboratory practice.
Related Research Compounds
Laboratories scaling up from the 500mg fill move to NAD+ 1000mg for bulk assay work. Parallel metabolic and redox studies frequently include Glutathione 1500mg, Humanin 10 mg and 5-Amino-1MQ 10mg, the last of which is studied as an NNMT inhibitor upstream of the NAD+ salvage route.
Why Researchers Source NAD+ from Dissolv Labs
Dissolv Labs is a research-supply company based in Southern California. Orders are picked, packed, and shipped domestically from our SoCal facility, so most U.S. laboratories see short transit times and no international customs delay.
Every vial ships as a complete kit. Each NAD+ vial is paired with its own bacteriostatic water reconstitution vial, so the material arrives ready to prepare in the lab without a separate diluent order. Compounds are supplied lyophilized in sealed, labeled vials with lot identification, and analytical documentation is available on request.
NAD+ 500mg — Frequently Asked Questions
What is NAD+ used for?
NAD+ is supplied strictly as a research chemical for in vitro and laboratory research applications. The literature uses it as a redox coenzyme in metabolic assays and as the required substrate for NAD+-consuming enzymes such as sirtuins and PARPs. It is not for human or veterinary use.
What is the difference between NAD+ and NADH?
NAD+ is the oxidised form, which accepts a hydride; NADH is the reduced form, which donates one. Only the oxidised NAD+ form is consumed as a substrate by sirtuins, PARPs and CD38, which is why assays of those enzymes specify NAD+ rather than NADH. The ratio between the two is itself a widely used experimental readout.
What does a NAD+ 500mg vial contain?
Each sealed vial holds 500mg of lyophilized NAD+ with lot identification on the label, packed with a matched bacteriostatic water vial for reconstitution at the bench. Vials are kept cold and shielded from light before preparation. Additional diluent is available as BAC Water 3ml.
Where can I buy NAD+ 500mg research grade?
NAD+ 500mg is available directly from Dissolv Labs and ships domestically from our Southern California facility, keeping transit short for U.S. laboratories. Each order arrives as a complete kit, and analytical documentation can be requested for any lot. Purchases are limited to qualified researchers for Research Use Only applications.
Research Use Only
NAD+ is sold exclusively as a Research Use Only (RUO) chemical. It is not a drug, supplement, cosmetic, or food, and it is not intended for human or veterinary use, ingestion, injection, topical application, or any form of consumption. It is intended solely for licensed laboratory research by qualified professionals. Dissolv Labs makes no medical, therapeutic, or diagnostic claims of any kind. By purchasing, the buyer confirms they are a qualified researcher and accepts full responsibility for lawful handling, use, and disposal.
Bacteriostatic (BAC) water is included free with every order.
Specifications
- Form: Lyophilized (freeze-dried) powder, sealed vial
- Appearance: White to off-white
- Purity: ≥99%, verified by HPLC
- Identity: Confirmed by mass spectrometry
- Testing: Independent third-party laboratory, every batch
- Documentation: Batch-specific COA available on request
Exact quantity and concentration are listed in the product title and variant options above. The figures above are release specifications — the measured result for your particular lot is stated on its Certificate of Analysis.
Documentation & Testing
Every batch is tested before release. Testing covers four checks: identity by mass spectrometry, purity by HPLC against a ≥99% release threshold, content verification against the labelled mass, and batch release tied to a specific lot number.
To request the Certificate of Analysis for your vial, email us with your order number or the lot number printed on the label. We do not gate documentation behind a form or a purchase.
New to reading a COA? Our plain-English guide decodes every line, and the full process is documented on our Quality & Testing page.
Handling & Storage
Lyophilized peptides are relatively stable during transit. Arriving at room temperature is not cause for concern — the cold pack is a margin of safety rather than a pass/fail condition.
Sealed vials of lyophilized material are typically stored refrigerated or frozen and protected from light. Handling protocols for a specific compound are determined by the researcher and their institution; we supply the material and its documentation.
Shipping & Returns
Orders placed before the daily cut-off are dispatched the same business day from Southern California in insulated packaging with ice packs. Tracking is issued at dispatch.
If a shipment arrives damaged, if vial contents appear inconsistent with the specification, or if the lot number on your vial does not match the certificate we provide, contact us and we will resolve it.
Because these are temperature-sensitive laboratory materials, opened vials cannot be returned to stock.
Questions
Straight answers about documentation, shipping, and what Research Use Only means.