Description
What Is CJC-1295 (No DAC)? (In Plain English)
The body has a gland that releases growth hormone when it gets a "go" message, and CJC-1295 (No DAC) is a lab-made copy of the first part of that message. Think of it as a short doorbell chime rather than the whole song — it rings, then fades quickly. Scientists study it in cells and animals to see how the gland answers a chime that does not last long.
CJC-1295 (No DAC) — Research Overview
CJC-1295 without DAC, widely referred to as Modified GRF (1-29), is a synthetic 29-amino-acid analog of the N-terminal fragment of growth hormone-releasing hormone. Four substitutions (commonly cited at positions 2, 8, 15 and 27) increase resistance to dipeptidyl peptidase-4 cleavage and improve stability relative to native GRF(1-29), while the absence of the drug affinity complex means it does not bind serum albumin and therefore has a short circulating profile in animal studies. Research interest centers on GHRH receptor engagement on somatotrophs and the pulsatile pattern of growth hormone release seen in preclinical models.
Primary Research Areas
- GHRH receptor pharmacology — studied for receptor binding and downstream cAMP signaling in vitro
- Growth hormone secretion dynamics — investigated in animal models for pulse amplitude and frequency
- GHRP synergy studies — frequently examined in combination with ghrelin-receptor agonists in preclinical work
- Peptide stability and enzymology — used to study DPP-4 resistance conferred by amino acid substitution
- IGF-1 axis research — measured for downstream markers of the somatotropic axis in rodent models
Specifications
- Compound: CJC-1295 without DAC (Modified GRF 1-29; tetrasubstituted GRF(1-29) analog)
- Molecular formula: C152H252N44O42
- Molecular weight: approx. 3367.9 g/mol
- Presentation: Lyophilized powder, sealed vial
- Quantity: 5 mg per vial
- Storage: Store lyophilized vials cold and protected from light. Reconstituted material is stored refrigerated per standard laboratory practice.
Related Research Peptides
CJC-1295 (No DAC) is one of the most studied secretagogue research compounds and is commonly compared with its long-acting counterpart. Related listings include CJC-1295 DAC 5 mg, Ipamorelin 5mg, Tesamorelin 5mg, and GHRP-2.
Why Researchers Source CJC-1295 (No DAC) from Dissolv Labs
Dissolv Labs is a research-supply company based in Southern California. Orders are picked, packed, and shipped domestically from our SoCal facility, so most U.S. laboratories see short transit times and no international customs delay.
Every vial ships as a complete kit. Each CJC-1295 (No DAC) vial is paired with its own bacteriostatic water reconstitution vial, so the material arrives ready to prepare in the lab without a separate diluent order. Compounds are supplied lyophilized in sealed, labeled vials with lot identification, and analytical documentation is available on request.
CJC-1295 (No DAC) — Frequently Asked Questions
What is CJC-1295 (No DAC) used for?
CJC-1295 (No DAC) is supplied strictly as a research chemical for in vitro and laboratory research applications. The literature studies it as a stabilized GHRH analog for investigating growth hormone secretion in cell and animal models. It is not for human or veterinary use.
What is the difference between CJC-1295 with DAC and without DAC?
The DAC version carries a drug affinity complex that binds reversibly to serum albumin, giving a much longer circulating profile in animal studies. The No DAC form lacks that modification, so preclinical data describe a short, pulse-like pattern of activity — which is why it is often chosen when researchers want to model physiological pulsatility rather than sustained exposure.
Is CJC-1295 (No DAC) the same as Mod GRF 1-29?
Yes — the two names refer to the same tetrasubstituted 29-residue GRF analog, and both appear throughout the literature and in supplier catalogs. Dissolv Labs lists it as CJC-1295 (No DAC) because that is the more common search term, with Mod GRF 1-29 given as a synonym on the specification list.
Where can I buy CJC-1295 No DAC 5mg research peptide?
Dissolv Labs stocks CJC-1295 (No DAC) 5mg and ships domestically from Southern California. Each vial is supplied lyophilized and lot-labeled as a complete kit with a bacteriostatic water reconstitution vial, with analytical documentation available on request.
Research Use Only
CJC-1295 (No DAC) is sold exclusively as a Research Use Only (RUO) chemical. It is not a drug, supplement, cosmetic, or food, and it is not intended for human or veterinary use, ingestion, injection, topical application, or any form of consumption. It is intended solely for licensed laboratory research by qualified professionals. Dissolv Labs makes no medical, therapeutic, or diagnostic claims of any kind. By purchasing, the buyer confirms they are a qualified researcher and accepts full responsibility for lawful handling, use, and disposal.
Bacteriostatic (BAC) water is included free with every order.
Specifications
- Form: Lyophilized (freeze-dried) powder, sealed vial
- Appearance: White to off-white
- Purity: ≥99%, verified by HPLC
- Identity: Confirmed by mass spectrometry
- Testing: Independent third-party laboratory, every batch
- Documentation: Batch-specific COA available on request
Exact quantity and concentration are listed in the product title and variant options above. The figures above are release specifications — the measured result for your particular lot is stated on its Certificate of Analysis.
Documentation & Testing
Every batch is tested before release. Testing covers four checks: identity by mass spectrometry, purity by HPLC against a ≥99% release threshold, content verification against the labelled mass, and batch release tied to a specific lot number.
To request the Certificate of Analysis for your vial, email us with your order number or the lot number printed on the label. We do not gate documentation behind a form or a purchase.
New to reading a COA? Our plain-English guide decodes every line, and the full process is documented on our Quality & Testing page.
Handling & Storage
Lyophilized peptides are relatively stable during transit. Arriving at room temperature is not cause for concern — the cold pack is a margin of safety rather than a pass/fail condition.
Sealed vials of lyophilized material are typically stored refrigerated or frozen and protected from light. Handling protocols for a specific compound are determined by the researcher and their institution; we supply the material and its documentation.
Shipping & Returns
Orders placed before the daily cut-off are dispatched the same business day from Southern California in insulated packaging with ice packs. Tracking is issued at dispatch.
If a shipment arrives damaged, if vial contents appear inconsistent with the specification, or if the lot number on your vial does not match the certificate we provide, contact us and we will resolve it.
Because these are temperature-sensitive laboratory materials, opened vials cannot be returned to stock.
Questions
Straight answers about documentation, shipping, and what Research Use Only means.