Description
What Is TB-500? (In Plain English)
TB-500 is a small piece of a natural protein called thymosin beta-4. Inside every cell there are tiny building rods called actin, and this peptide helps decide when those rods get built up or taken apart — rather like a foreman calling out when to raise or drop the scaffolding. Scientists study it in cell dishes and in animals to watch how tissue rearranges itself while it repairs.
TB-500 — Research Overview
TB-500 is the research designation for a synthetic peptide related to thymosin β-4 (Tβ4), a 43-amino-acid G-actin-sequestering protein found in most mammalian cell types. Research material is supplied either as the full-length Tβ4 sequence or as an acetylated fragment centered on the LKKTETQ actin-binding motif, which the literature identifies as the minimal region responsible for actin monomer binding. Published work associates Tβ4 with cytoskeletal remodeling, cell migration, and angiogenic signaling in vitro and in animal models.
Primary Research Areas
- Actin cytoskeleton dynamics — investigated in vitro for G-actin sequestering and monomer-pool regulation
- Cell migration — studied in scratch and transwell assays using keratinocyte and endothelial lines
- Angiogenesis — examined in tube-formation and aortic-ring models for vessel-sprouting endpoints
- Cardiac remodeling — referenced in rodent models of post-infarct tissue reorganization
- Inflammatory signaling — investigated for cytokine-profile changes in cultured immune cells
Specifications
- Compound: TB-500 (synthetic thymosin β-4 derivative; Tβ4 fragment)
- CAS: Not assigned
- Presentation: Lyophilized powder, sealed vial
- Quantity: Single vial, quantity as listed on this product page
- Storage: Store lyophilized vials cold and protected from light. Reconstituted material is stored refrigerated per standard laboratory practice.
Related Research Peptides
TB-500 is a mainstay of the tissue-repair research area and is routinely studied against and alongside other repair-associated peptides. Related catalog listings include BPC-157, BPC-157 + TB-500 Combo (Stack), KPV, and GHK-Cu.
Why Researchers Source TB-500 from Dissolv Labs
Dissolv Labs is a research-supply company based in Southern California. Orders are picked, packed, and shipped domestically from our SoCal facility, so most U.S. laboratories see short transit times and no international customs delay.
Every vial ships as a complete kit. Each TB-500 vial is paired with its own bacteriostatic water reconstitution vial, so the material arrives ready to prepare in the lab without a separate diluent order. Compounds are supplied lyophilized in sealed, labeled vials with lot identification, and analytical documentation is available on request.
TB-500 — Frequently Asked Questions
What is TB-500 used for?
TB-500 is supplied strictly as a research chemical for in vitro and laboratory research applications. The literature studies it as a thymosin β-4 derivative in actin-binding, cell-migration, and angiogenesis assays. It is not for human or veterinary use.
How does TB-500 differ from BPC-157?
They are unrelated sequences studied in overlapping research areas. TB-500 derives from thymosin β-4 and is characterized primarily through actin sequestering and cytoskeletal dynamics, while BPC-157 is a gastric-juice-derived pentadecapeptide associated in the literature with angiogenic and growth-factor signaling. Laboratories frequently run them in parallel, which is why combination listings exist in the catalog.
What form does TB-500 ship in?
TB-500 ships as a lyophilized powder in a sealed, lot-labeled vial, stored cold and shielded from light. Every kit includes a matched bacteriostatic water vial so reconstitution can be carried out in the lab without ordering diluent separately. Reconstituted material is refrigerated per standard laboratory practice.
Where can I buy TB-500 research peptide?
TB-500 is available for sale from Dissolv Labs, a Southern California research-supply company. Orders are shipped domestically from our SoCal facility as a complete kit with reconstitution vial included. Analytical documentation is available on request for qualified laboratories.
Research Use Only
TB-500 is sold exclusively as a Research Use Only (RUO) chemical. It is not a drug, supplement, cosmetic, or food, and it is not intended for human or veterinary use, ingestion, injection, topical application, or any form of consumption. It is intended solely for licensed laboratory research by qualified professionals. Dissolv Labs makes no medical, therapeutic, or diagnostic claims of any kind. By purchasing, the buyer confirms they are a qualified researcher and accepts full responsibility for lawful handling, use, and disposal.
Bacteriostatic (BAC) water is included free with every order.
Specifications
- Form: Lyophilized (freeze-dried) powder, sealed vial
- Appearance: White to off-white
- Purity: ≥99%, verified by HPLC
- Identity: Confirmed by mass spectrometry
- Testing: Independent third-party laboratory, every batch
- Documentation: Batch-specific COA available on request
Exact quantity and concentration are listed in the product title and variant options above. The figures above are release specifications — the measured result for your particular lot is stated on its Certificate of Analysis.
Documentation & Testing
Every batch is tested before release. Testing covers four checks: identity by mass spectrometry, purity by HPLC against a ≥99% release threshold, content verification against the labelled mass, and batch release tied to a specific lot number.
To request the Certificate of Analysis for your vial, email us with your order number or the lot number printed on the label. We do not gate documentation behind a form or a purchase.
New to reading a COA? Our plain-English guide decodes every line, and the full process is documented on our Quality & Testing page.
Handling & Storage
Lyophilized peptides are relatively stable during transit. Arriving at room temperature is not cause for concern — the cold pack is a margin of safety rather than a pass/fail condition.
Sealed vials of lyophilized material are typically stored refrigerated or frozen and protected from light. Handling protocols for a specific compound are determined by the researcher and their institution; we supply the material and its documentation.
Shipping & Returns
Orders placed before the daily cut-off are dispatched the same business day from Southern California in insulated packaging with ice packs. Tracking is issued at dispatch.
If a shipment arrives damaged, if vial contents appear inconsistent with the specification, or if the lot number on your vial does not match the certificate we provide, contact us and we will resolve it.
Because these are temperature-sensitive laboratory materials, opened vials cannot be returned to stock.
Questions
Straight answers about documentation, shipping, and what Research Use Only means.