Description
What Is 5-Amino-1MQ? (In Plain English)
Every cell keeps a little helper molecule called NAD+ on hand, a bit like a battery charger for the tiny engines that make energy. One busy enzyme in fat cells keeps grabbing the spare parts needed to build those chargers. 5-Amino-1MQ is a small molecule that scientists add to cells in the lab to slow that enzyme down and watch what happens next.
5-Amino-1MQ — Research Overview
5-Amino-1MQ is a small-molecule quinolinium compound rather than a peptide, and it is referenced in the literature as a cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT methylates nicotinamide and diverts it away from the NAD+ salvage pathway, so inhibiting the enzyme is investigated in vitro as a way to alter intracellular nicotinamide and NAD+ pools. Published work on 5-Amino-1MQ is concentrated in adipocyte cultures, skeletal muscle preparations, and diet-induced obesity models in mice.
Primary Research Areas
- NNMT enzyme inhibition — studied as a tool compound for probing NNMT activity and selectivity in vitro
- NAD+ salvage biochemistry — investigated for how blocking nicotinamide methylation shifts cellular NAD+ pools
- Adipocyte metabolism — examined in cultured adipocytes and in rodent adipose tissue models
- Skeletal muscle and aging models — referenced in animal work on muscle stem cell function in aged mice
- Metabolic phenotyping — used as a comparator in preclinical metabolic research panels
Specifications
- Compound: 5-Amino-1MQ (5-amino-1-methylquinolinium; NNMT inhibitor)
- Presentation: Lyophilized powder, sealed vial
- Quantity: 10 mg per vial
- Storage: Store lyophilized vials cold and protected from light. Reconstituted material is stored refrigerated per standard laboratory practice.
Related Research Peptides
Laboratories working on NAD+ biology and mitochondrial metabolism frequently run 5-Amino-1MQ alongside related catalog compounds. Common pairings include NAD+ 500mg, MOTS-c 10mg, SLU-PP-332, and L-Carnitine 1200mg.
Why Researchers Source 5-Amino-1MQ from Dissolv Labs
Dissolv Labs is a research-supply company based in Southern California. Orders are picked, packed, and shipped domestically from our SoCal facility, so most U.S. laboratories see short transit times and no international customs delay.
Every vial ships as a complete kit. Each 5-Amino-1MQ vial is paired with its own bacteriostatic water reconstitution vial, so the material arrives ready to prepare in the lab without a separate diluent order. Compounds are supplied lyophilized in sealed, labeled vials with lot identification, and analytical documentation is available on request.
5-Amino-1MQ — Frequently Asked Questions
What is 5-Amino-1MQ used for?
5-Amino-1MQ is supplied strictly as a research chemical for in vitro and laboratory research applications. The literature investigates it as an NNMT inhibitor in adipocyte, skeletal muscle, and rodent metabolic models. It is not for human or veterinary use.
Is 5-Amino-1MQ a peptide?
No. Despite being catalogued alongside research peptides, 5-Amino-1MQ is a small-molecule quinolinium derivative with no amino acid backbone. It is grouped with metabolic research compounds because it is studied in the same NAD+ and adipose tissue research areas.
How is 5-Amino-1MQ shipped and stored?
Material ships as a lyophilized powder in a sealed, lot-labeled vial, accompanied by its own bacteriostatic water reconstitution vial. Vials should be kept cold and shielded from light until prepared. Once reconstituted, solutions are held refrigerated per standard laboratory practice.
Where can I buy 5-Amino-1MQ research compound?
Dissolv Labs supplies 5-Amino-1MQ 10mg to qualified laboratories from our Southern California facility. Every order ships domestically as a complete kit with a matched reconstitution vial and lot identification. Analytical documentation can be requested at the time of ordering.
Research Use Only
5-Amino-1MQ is sold exclusively as a Research Use Only (RUO) chemical. It is not a drug, supplement, cosmetic, or food, and it is not intended for human or veterinary use, ingestion, injection, topical application, or any form of consumption. It is intended solely for licensed laboratory research by qualified professionals. Dissolv Labs makes no medical, therapeutic, or diagnostic claims of any kind. By purchasing, the buyer confirms they are a qualified researcher and accepts full responsibility for lawful handling, use, and disposal.
Bacteriostatic (BAC) water is included free with every order.
Specifications
- Form: Lyophilized (freeze-dried) powder, sealed vial
- Appearance: White to off-white
- Purity: ≥99%, verified by HPLC
- Identity: Confirmed by mass spectrometry
- Testing: Independent third-party laboratory, every batch
- Documentation: Batch-specific COA available on request
Exact quantity and concentration are listed in the product title and variant options above. The figures above are release specifications — the measured result for your particular lot is stated on its Certificate of Analysis.
Documentation & Testing
Every batch is tested before release. Testing covers four checks: identity by mass spectrometry, purity by HPLC against a ≥99% release threshold, content verification against the labelled mass, and batch release tied to a specific lot number.
To request the Certificate of Analysis for your vial, email us with your order number or the lot number printed on the label. We do not gate documentation behind a form or a purchase.
New to reading a COA? Our plain-English guide decodes every line, and the full process is documented on our Quality & Testing page.
Handling & Storage
Lyophilized peptides are relatively stable during transit. Arriving at room temperature is not cause for concern — the cold pack is a margin of safety rather than a pass/fail condition.
Sealed vials of lyophilized material are typically stored refrigerated or frozen and protected from light. Handling protocols for a specific compound are determined by the researcher and their institution; we supply the material and its documentation.
Shipping & Returns
Orders placed before the daily cut-off are dispatched the same business day from Southern California in insulated packaging with ice packs. Tracking is issued at dispatch.
If a shipment arrives damaged, if vial contents appear inconsistent with the specification, or if the lot number on your vial does not match the certificate we provide, contact us and we will resolve it.
Because these are temperature-sensitive laboratory materials, opened vials cannot be returned to stock.
Questions
Straight answers about documentation, shipping, and what Research Use Only means.