Description
What Is Semax 10mg? (In Plain English)
Semax is a short chain of seven amino acids copied from a small piece of a natural brain signalling protein. Chemists added a three-part tail so enzymes cannot snip it apart as quickly, the way a knot at the end of a thread stops it unravelling. Scientists give it to rats and mice, or add it to brain cells in a dish, to study memory, attention, and how nerve cells cope with stress.
Semax 10mg — Research Overview
Semax is a synthetic heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro, consisting of the ACTH(4-7) fragment extended at the C-terminus with Pro-Gly-Pro to slow enzymatic degradation. Because the corticotropic portion of ACTH is absent, the literature describes it as devoid of hormonal activity while retaining neuroactive properties. Reported research associations include upregulation of BDNF and NGF expression in rodent brain tissue, modulation of monoaminergic and cholinergic systems, and inhibition of enkephalin-degrading enzymes.
Primary Research Areas
- Neurotrophic factor expression — BDNF and NGF transcript and protein changes in rodent hippocampus
- Cerebral ischemia models — investigated in rodent middle cerebral artery occlusion paradigms
- Learning and attention paradigms — maze and avoidance-task performance in animal studies
- Monoamine and cholinergic modulation — dopamine and serotonin turnover measured in brain tissue
- Peptide stability chemistry — Pro-Gly-Pro extension as a protease-resistance strategy for short peptides
Specifications
- Compound: Semax (Met-Glu-His-Phe-Pro-Gly-Pro; MEHFPGP; ACTH(4-7) analog)
- CAS: 80714-61-0
- Molecular formula: C37H51N9O10S
- Molecular weight: ~813.9 g/mol
- Presentation: Lyophilized powder, sealed vial
- Quantity: 10mg per vial
- Storage: Store lyophilized vials cold and protected from light. Reconstituted material is stored refrigerated per standard laboratory practice.
Related Research Peptides
Semax is routinely studied alongside Selank 10mg, its sister Pro-Gly-Pro-stabilized regulatory heptapeptide, in matched behavioural panels. Neuro-focused laboratories also reference P21 5mg, Cerebrolysin, and PE-22-28 when assembling comparative neuroprotection or neurogenesis study designs.
Why Researchers Source Semax 10mg from Dissolv Labs
Dissolv Labs is a research-supply company based in Southern California. Orders are picked, packed, and shipped domestically from our SoCal facility, so most U.S. laboratories see short transit times and no international customs delay.
Every vial ships as a complete kit. Each Semax 10mg vial is paired with its own bacteriostatic water reconstitution vial, so the material arrives ready to prepare in the lab without a separate diluent order. Compounds are supplied lyophilized in sealed, labeled vials with lot identification, and analytical documentation is available on request.
Semax 10mg — Frequently Asked Questions
What is Semax 10mg used for?
Semax 10mg is supplied strictly as a research chemical for in vitro and laboratory research applications. The literature investigates it in rodent models of cerebral ischemia, in cognition and attention paradigms, and in studies of BDNF and NGF expression. It is not for human or veterinary use.
Semax vs Selank — which does the literature treat as the cognitive comparator?
Semax derives from the ACTH(4-7) fragment and is the compound more often placed in learning, attention, and neuroprotection paradigms. Selank derives from the immune tetrapeptide tuftsin and appears more frequently in anxiety-related behavioural and GABAergic studies. Both share the Pro-Gly-Pro stabilizing extension, which is why they are so often published as a pair.
Does Semax retain any hormonal activity from ACTH?
The fragment used in Semax covers residues 4 to 7 of ACTH, which excludes the region responsible for corticotropic signaling. The literature accordingly characterizes it as non-hormonal, and studies focus on its neuroactive rather than endocrine associations. That separation is a large part of why the analog was developed.
Where can I buy Semax research peptide?
Dissolv Labs supplies Semax 10mg to qualified researchers, shipping domestically from our Southern California facility so U.S. laboratories see short transit and no customs delay. Every order arrives as a complete kit with its bacteriostatic water reconstitution vial included. Analytical documentation for the supplied lot is available on request.
Research Use Only
Semax 10mg is sold exclusively as a Research Use Only (RUO) chemical. It is not a drug, supplement, cosmetic, or food, and it is not intended for human or veterinary use, ingestion, injection, topical application, or any form of consumption. It is intended solely for licensed laboratory research by qualified professionals. Dissolv Labs makes no medical, therapeutic, or diagnostic claims of any kind. By purchasing, the buyer confirms they are a qualified researcher and accepts full responsibility for lawful handling, use, and disposal.
Bacteriostatic (BAC) water is included free with every order.
Specifications
- Form: Lyophilized (freeze-dried) powder, sealed vial
- Appearance: White to off-white
- Purity: ≥99%, verified by HPLC
- Identity: Confirmed by mass spectrometry
- Testing: Independent third-party laboratory, every batch
- Documentation: Batch-specific COA available on request
Exact quantity and concentration are listed in the product title and variant options above. The figures above are release specifications — the measured result for your particular lot is stated on its Certificate of Analysis.
Documentation & Testing
Every batch is tested before release. Testing covers four checks: identity by mass spectrometry, purity by HPLC against a ≥99% release threshold, content verification against the labelled mass, and batch release tied to a specific lot number.
To request the Certificate of Analysis for your vial, email us with your order number or the lot number printed on the label. We do not gate documentation behind a form or a purchase.
New to reading a COA? Our plain-English guide decodes every line, and the full process is documented on our Quality & Testing page.
Handling & Storage
Lyophilized peptides are relatively stable during transit. Arriving at room temperature is not cause for concern — the cold pack is a margin of safety rather than a pass/fail condition.
Sealed vials of lyophilized material are typically stored refrigerated or frozen and protected from light. Handling protocols for a specific compound are determined by the researcher and their institution; we supply the material and its documentation.
Shipping & Returns
Orders placed before the daily cut-off are dispatched the same business day from Southern California in insulated packaging with ice packs. Tracking is issued at dispatch.
If a shipment arrives damaged, if vial contents appear inconsistent with the specification, or if the lot number on your vial does not match the certificate we provide, contact us and we will resolve it.
Because these are temperature-sensitive laboratory materials, opened vials cannot be returned to stock.
Questions
Straight answers about documentation, shipping, and what Research Use Only means.