{"product_id":"mots-c","title":"MOTS-c","description":"\u003c!-- =========================================================\n  MOTS-c — DISSOLV LABS\n  Mitochondrial-derived peptide\n  10 mg lyophilized vial\n  Shopify product description — paste into the Code View\n  of the product description field.\n========================================================= --\u003e\n\u003ch2\u003eMOTS-c — Mitochondrial-Derived Research Peptide\u003c\/h2\u003e\n\u003cp\u003eMOTS-c is a 16-amino-acid synthetic peptide referenced in scientific literature as a \u003cstrong\u003emitochondrial-derived peptide\u003c\/strong\u003e (MDP) encoded within the mitochondrial 12S rRNA. It is one of the most extensively profiled compounds within the emerging mitochondrial-nuclear signaling research category. DISSOLV LABS supplies MOTS-c as a \u003cstrong\u003e10 mg\u003c\/strong\u003e lyophilized vial — a high-purity analytical reference compound for qualified laboratory research professionals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% (HPLC-MS verified)\u003cbr\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e 10 mg lyophilized vial, sealed amber glass\u003cbr\u003e\u003cstrong\u003eDesignation:\u003c\/strong\u003e Research use only — not intended for human or veterinary use\u003c\/p\u003e\n\u003ch2\u003eCompound Overview\u003c\/h2\u003e\n\u003cp\u003eMOTS-c (an acronym derived from \u003cstrong\u003eMitochondrial Open Reading frame of the Twelve S rRNA-c\u003c\/strong\u003e) is a short peptide encoded within the mitochondrial genome rather than the nuclear genome — a distinguishing characteristic that places it within the small but rapidly expanding family of mitochondrial-derived peptides. Within the published literature, MOTS-c is most commonly studied within AMPK pathway research, mitochondrial-nuclear signaling research, and metabolic homeostasis research models.\u003c\/p\u003e\n\u003cp\u003eMOTS-c is frequently positioned alongside other mitochondrial-derived peptides such as \u003cstrong\u003eHumanin\u003c\/strong\u003e and the \u003cstrong\u003eSHLP\u003c\/strong\u003e family (Small Humanin-Like Peptides), and is studied in adjacency to mitochondrial-targeted research compounds including \u003cstrong\u003eSS-31\u003c\/strong\u003e (Elamipretide). It is a foundational reference compound in the broader mitochondrial biology and longevity research literature.\u003c\/p\u003e\n\u003ch2\u003eResearch Context\u003c\/h2\u003e\n\u003cp\u003eMOTS-c has been investigated in published preclinical and clinical research and is commonly referenced in laboratory work involving:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondrial-derived peptide (MDP) biology\u003c\/li\u003e\n\u003cli\u003eAMPK (AMP-activated protein kinase) pathway research\u003c\/li\u003e\n\u003cli\u003eMitochondrial-nuclear retrograde signaling research\u003c\/li\u003e\n\u003cli\u003eMetabolic homeostasis and glucose metabolism research models\u003c\/li\u003e\n\u003cli\u003eExercise physiology and muscle bioenergetics research\u003c\/li\u003e\n\u003cli\u003eAging biology and longevity research domains\u003c\/li\u003e\n\u003cli\u003eComparative mitochondrial peptide research (Humanin, SHLP family)\u003c\/li\u003e\n\u003cli\u003eFolate-cycle and methionine-cycle research models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eScientific Classification\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCompound name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMOTS-c\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFull name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMitochondrial Open Reading frame of the Twelve S rRNA-c\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular class\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSynthetic peptide (16 amino acids)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eGenetic origin\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEncoded within the mitochondrial 12S rRNA gene\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFunctional category\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMitochondrial-derived peptide (MDP); AMPK pathway research compound\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePeptide family\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMitochondrial-derived peptide family (with Humanin, SHLP-1 through SHLP-6)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eResearch domains\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMitochondrial biology, AMPK signaling, metabolic homeostasis, exercise physiology, mitochondrial-nuclear signaling, aging biology\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAdjacent compounds\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHumanin, SHLP peptides, SS-31 (Elamipretide), NAD+, NMN, Epitalon, Spermidine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eAnalytical \u0026amp; Quality Standards\u003c\/h2\u003e\n\u003cp\u003eEvery MOTS-c lot supplied by DISSOLV LABS undergoes a structured analytical workflow designed to confirm identity, purity, and batch consistency before release.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity verification\u003c\/strong\u003e by reversed-phase high-performance liquid chromatography (RP-HPLC)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdentity confirmation\u003c\/strong\u003e by mass spectrometry (HPLC-MS)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResidual solvent and moisture screening\u003c\/strong\u003e to documented thresholds\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBatch-to-batch consistency\u003c\/strong\u003e recorded on a per-lot Certificate of Analysis (COA)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-party verification\u003c\/strong\u003e available upon institutional request\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterile lyophilization\u003c\/strong\u003e under inert conditions to preserve peptide integrity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTechnical Specifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 mg lyophilized vial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAmino acid count\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e16\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAppearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUniform, free-flowing white lyophilized solid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePackaging\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSealed amber glass vial, crimped seal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCatalog identifier\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDSL-MOTSC-010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≥99% (HPLC-MS verified)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRecommended storage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e−20 °C, protected from light and moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSterile or bacteriostatic solvent (laboratory protocol only)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStability\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStable under recommended storage conditions; refer to lot COA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHandling\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRestricted to qualified research personnel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat is MOTS-c?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c is a 16-amino-acid synthetic peptide referenced in scientific literature as a mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene. It is supplied by DISSOLV LABS as an analytical reference compound for laboratory research use only.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat does MOTS-c stand for?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c is an acronym for \u003cstrong\u003eMitochondrial Open Reading frame of the Twelve S rRNA-c\u003c\/strong\u003e — referencing the peptide's genetic origin within the mitochondrial 12S rRNA gene rather than the nuclear genome.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat is a mitochondrial-derived peptide?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMitochondrial-derived peptides (MDPs) are a class of short peptides encoded within the mitochondrial genome rather than the nuclear genome. The family includes MOTS-c, Humanin, and the SHLP-1 through SHLP-6 peptides. MDPs are studied in published research literature as endogenous signaling molecules involved in mitochondrial-nuclear retrograde communication.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat category does MOTS-c belong to?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c is classified within the mitochondrial-derived peptide family. In the research literature it is most commonly studied within AMPK pathway research, mitochondrial-nuclear signaling research, and metabolic homeostasis research.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eHow does MOTS-c differ from Humanin and SHLP peptides?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c, Humanin, and the SHLP-1 through SHLP-6 peptides are all members of the mitochondrial-derived peptide family, each encoded within distinct regions of the mitochondrial genome. They occupy related but distinct positions in published research literature, with MOTS-c most prominently associated with AMPK pathway research and Humanin most prominently associated with cytoprotection research.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eHow does MOTS-c relate to NAD+ and NMN?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c and NAD+\/NMN are studied in overlapping research domains — both are referenced in published mitochondrial biology, metabolic homeostasis, and longevity research literature. MOTS-c is a mitochondrial-derived peptide; NAD+ is a pyridine nucleotide coenzyme; they represent distinct molecular classes that researchers commonly investigate side by side within mitochondrial bioenergetics research.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat purity standard does DISSOLV LABS supply?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eDISSOLV LABS supplies MOTS-c at \u003cstrong\u003e≥99% purity\u003c\/strong\u003e, verified by reversed-phase HPLC and confirmed by mass spectrometry (HPLC-MS). Each lot is accompanied by a Certificate of Analysis.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat analytical testing is performed on each lot?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eEach MOTS-c lot is subjected to RP-HPLC purity analysis, HPLC-MS identity confirmation, residual solvent and moisture screening, and batch-consistency documentation. Third-party analytical verification is available upon institutional request.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eHow should MOTS-c be stored?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eRecommended storage is \u003cstrong\u003e−20 °C\u003c\/strong\u003e, protected from light and moisture, in the original sealed vial. Refer to the lot-specific Certificate of Analysis for stability data.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eHow is MOTS-c reconstituted for laboratory work?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c is typically reconstituted with sterile or bacteriostatic solvent in accordance with the receiving laboratory's internal protocols. Reconstitution methodology is the responsibility of the qualified research professional.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eIs MOTS-c research use only?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eYes. MOTS-c supplied by DISSOLV LABS is \u003cstrong\u003estrictly for laboratory research use only\u003c\/strong\u003e. It is not intended for human or veterinary use, and is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWhat compounds are related to MOTS-c?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c is commonly referenced alongside other mitochondrial-derived peptides (Humanin, SHLP-1 through SHLP-6), mitochondrial-targeted research compounds (SS-31 \/ Elamipretide), pyridine nucleotide coenzymes (NAD+, NMN, NR), and broader longevity research compounds including Epitalon and Spermidine.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eIs a Certificate of Analysis (COA) available?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eYes. Every lot is shipped with a lot-specific Certificate of Analysis documenting purity, identity, and analytical methodology. COAs are available to verified research accounts on request.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003e\u003cstrong\u003eWho should handle MOTS-c?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cp\u003eMOTS-c is intended exclusively for handling by qualified laboratory research professionals operating within appropriate research facilities. It is not for sale to or use by the general public.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003ch2\u003eRelated Research Compounds\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHumanin\u003c\/strong\u003e — mitochondrial-derived peptide research compound\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHLP peptides\u003c\/strong\u003e — Small Humanin-Like Peptides (SHLP-1 through SHLP-6); mitochondrial-derived peptide family members\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSS-31 (Elamipretide)\u003c\/strong\u003e — mitochondrial-targeted research peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+\u003c\/strong\u003e — pyridine nucleotide coenzyme; mitochondrial bioenergetics research\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNMN\u003c\/strong\u003e (Nicotinamide Mononucleotide) — NAD+ biosynthetic precursor research compound\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpitalon\u003c\/strong\u003e — synthetic tetrapeptide research compound studied in telomerase and longevity research\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpermidine\u003c\/strong\u003e — polyamine research compound studied in autophagy and longevity research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e This product is not intended for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Sale and distribution are restricted to qualified laboratory research professionals operating within appropriate research environments. The purchaser assumes full responsibility for safe handling, storage, and disposal in accordance with applicable institutional, local, and federal guidelines.\u003c\/p\u003e","brand":"Dissolv Labs","offers":[{"title":"Default Title","offer_id":52102007619864,"sku":"DSL-MOTSC-010","price":35.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0987\/0861\/9544\/files\/MOTS-c10mg.png?v=1779640231","url":"https:\/\/dissolv.com\/products\/mots-c","provider":"Dissolv Labs","version":"1.0","type":"link"}